Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report

نویسندگان

  • Mukremin Uysal
  • Sema Sezgin Goksu
  • Hasan Senol Coskun
  • Burhan Savas
  • Mustafa Ozdogan
  • Hakan Bozcuk
چکیده

INTRODUCTION Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problems, gastrointestinal perforation, proteinuria and hypertension. CASE PRESENTATION We present the case of a 65-year old Asian man with synovial metastasis of the knee who experienced intraarticular hemorrhage after bevacizumab treatment. He presented with monoarthritis of the left knee. CONCLUSION Bevacizumab-related hemorrhage can cause serious morbidity and unusual sites of hemorrhage may be seen.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2012